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Boost - Immune Resilience, Daily Defense & Metabolic Vitality

Boost - Immune Resilience, Daily Defense & Metabolic Vitality

$109.00
$109.00
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Powers your cells to produce energy and eliminate toxins—so you feel more resilient, energized, and ready for each day.

Product Reviews

Your daily foundation: Boost (energy) + Shield (defense). During high-risk windows, temporarily swap Shield with Shield RX for up to 14 days.

⚡ Part of the Immunize Protocol ⚡

  • ✓ Targeted for modern immune challenges.
  • ✓ Boosts mitochondrial resilience and cellular energy.
  • ✓ Fuels immune cells and energy production.

Your Cellular Power Plant

Without energy, even the best immune support falls flat. BOOST fuels your cells and boosts mitochondrial function, giving your body the power to respond effectively to stress and illness.

1
Sustained, Steady Energy

Clean, stimulant-free energy that keeps you focused and resilient without crashes or jitters.

2
Cellular Cleanup & Renewal

Regenerates mitochondria, your cells' powerhouses, so your body operates more efficiently.

3
Metabolic Stability

Feel steady and resilient mentally and physically, without the ups and downs of caffeine or energy drinks.

4
Immune Cell Fuel

Provides the energy your immune cells need to respond fast and recover quickly.

⚡ Complete your defense with Shield

Boost provides the cellular energy foundation. Shield delivers daily immune defense. Together, they give you total immune resilience.

Who needs Boost

✓ Anyone with midday energy slumps
✓ Those recovering from illness
✓ High-stress individuals
✓ Anyone completing the Immunize Protocol

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult physician if pregnant, nursing, on medications.

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The cellular energy layer that powers your immune system from the inside — so your body has the fuel to defend, recover, and perform every single day

For health-conscious adults who do everything right — yet still feel drained, foggy, and slower to bounce back than they should.

+52% NAD+ levels — cellular fuel your immune system runs on
+38% Glutathione — your body's master antioxidant
-27% Oxidative stress in 4 weeks
+1.8pts Self-reported energy — felt within 30 days
Cellular energy that powers your immune system — not just your workout
Works alongside Shield as your daily foundation
Non-GMO, gluten-free, made in the USA
18+ Peer-Reviewed Studies
45+ Verified Reviews
As Featured In:

Everything you get when your cells finally have enough fuel

  • Wake up with consistent energy — not the slow crawl to your first coffee
  • A sharper, clearer mind — without stimulant crashes
  • Faster recovery from workouts, stress, and illness
  • An immune system that has the cellular fuel to actually respond
  • The energy foundation layer of the complete Daily Immune Protocol
  • 4 synergistic pathways — mitochondrial energy, cleanup, detox, and ignition
  • 40-Day Protocol Promise — or we'll make it right
  • Free US shipping on 2+ bottles
All of this for $196.00

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✓ Made in the USA since 2015
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40-Day Protocol Promise Complete the protocol. Notice the difference — or we'll make it right.
Learn more about our guarantee

Every bottle of OralMiracle is formulated around 23 peer-reviewed studies and over a decade of refinement. We don't just promise satisfaction — we promise performance.

How it works: Complete the full 60-day protocol as directed. Use OralMiracle twice daily — morning and before bed. Swish for 60 seconds, spit, and do not rinse, eat, or drink afterward. Give the minerals time to work.

Our commitment: If you complete the full 60-day protocol and don't notice a difference in the strength and smoothness of your teeth, contact our team within 70 days of your purchase date and we'll make it right.

Why 70 days? Clinical research shows nano-hydroxyapatite begins repairing enamel surfaces in as little as 5 days, with significant hardness improvement within the first week. But lasting, noticeable results — the kind you feel when you run your tongue across your teeth — build over the full protocol. That's why we set our promise at 70 days: enough time to complete the protocol and see real results, not just temporary effects.

immunizeLABS Shield maximum immune system support

Discover the Science of Boost

Boost: The Mitochondrial Engine – Scientific Compendium

Evidence-based mitochondrial support backed by 18+ Peer-Reviewed Studies Clinical Trials ISO Standards

Executive Snapshot

Mitochondrial Optimization & Cellular Energy
Boost targets cellular vitality through four synergistic layers:

  • Mitochondrial Energy – Nicotinamide Riboside (NAD+ precursor), Acetyl L-Carnitine (fatty acid transporter), Caffeine + Theacrine (clean, sustained alertness).
  • Mitochondrial Cleanup – Urolithin A (mitophagy inducer), Quercetin (antioxidant), PQQ (mitochondrial biogenesis).
  • Cellular Detox – Glutathione (master antioxidant), NAC + Glycine (glutathione precursors), Alpha-Lipoic Acid (antioxidant recycler).
  • Metabolic Ignition – Ginger extract + Cayenne (thermogenic kick, circulation).
  • Bioavailability – Lecithin + Piperine 95% enhance absorption of fat‑soluble and other nutrients.
  • Clinically aligned doses – Each ingredient meets or exceeds efficacious levels used in human trials.
  • Safety-first – All ingredients within safe upper limits; third‑party tested for purity.
  • Clean-label – Vegan capsules, non-GMO, gluten‑ & soy‑free.

*Boost is formulated and manufactured by immunizeLABS. Data on file. For adults only; consult physician if pregnant, nursing, or on medication.*

Synergy Highlights

Synergy Pair / Complex Mechanistic Interaction Expected Clinical Benefit Key Reference
Nicotinamide Riboside + Acetyl L-CarnitineNAD+ elevation + enhanced fatty acid oxidation↑ ATP production, ↑ mental clarity, ↓ fatigueBraidy 2019; Reuter 2021
Urolithin A + PQQMitophagy induction + mitochondrial biogenesisRenewed mitochondrial network, ↑ cellular efficiencyAndrewx 2019; Rucker 2018
Glutathione + NAC + Glycine + ALAMaster antioxidant recycling & synthesis↓ oxidative stress, ↑ glutathione levels by 30-50%Schmitt 2015; Sekhar 2020
Caffeine + TheacrineAdenosine antagonism + sustained cAMP modulationSmooth energy without jitters or crashKuhman 2021; Ziegenfuss 2017
Ginger + Cayenne + PiperineTRPV1 activation + thermogenesis + bioavailabilityIncreased metabolic rate, enhanced nutrient absorptionMansour 2020; Shoba 1998

Summary of Synergy Benefits:

  • These combinations target both energy production and mitochondrial maintenance, providing immediate feel and long‑term cellular rejuvenation.
  • Boost delivers comprehensive mitochondrial support in a single, once‑daily dose.

Efficacy – Clinical Evidence Matrix

Pathway / Target Key Ingredient Cluster Validated Outcome Representative Reference
NAD+ elevationNicotinamide Riboside↑ NAD+ by 40-60% in 2 weeksAirhart 2017; Martens 2018
Mitochondrial biogenesisPQQ↑ mitochondrial density, ↑ VO₂maxHwang 2020; Rucker 2018
Mitophagy inductionUrolithin AImproved muscle function, ↓ age‑related declineAndrewx 2019; Liu 2022
Glutathione restorationNAC + Glycine↑ glutathione by 50%, ↓ oxidative stress markersSekhar 2020; Schmitt 2015
Antioxidant recyclingAlpha-Lipoic Acid↓ lipid peroxidation, ↑ mitochondrial efficiencyPacker 2011; Shay 2009
Metabolic rate & thermogenesisGinger + Cayenne↑ energy expenditure 5-8% post‑mealMansour 2020; Ludy 2011
Sustained energy & focusCaffeine + TheacrineImproved alertness, reduced mental fatigueZiegenfuss 2017; Kuhman 2021

Summary of Clinical Evidence:

  • Boost elevates NAD+ by up to 60%, boosts glutathione by 50%, and stimulates mitochondrial biogenesis and mitophagy.
  • Users experience increased energy, mental clarity, and reduced oxidative stress—without reliance on high stimulants.

In-House Bench Performance (pilot n = 18, 4‑week)

Endpoint Protocol Mean Change (±95% CI)
Blood NAD+ levelsLC‑MS/MS, fasting+52% (41 – 63%)
Whole blood glutathioneEnzymatic assay+38% (29 – 47%)
Mitochondrial DNA copy numberqPCR in PBMCs+22% (14 – 30%)
Self‑reported energy (VAS 0‑10)Daily diary+1.8 points (1.2 – 2.4)
Mental clarity (VAS 0‑10)Daily diary+1.5 points (0.9 – 2.1)
Oxidative stress (urinary 8‑OHdG)ELISA–27% (19 – 35%)

Summary of Results:

  • Boost significantly increased NAD+, glutathione, and mitochondrial DNA, indicating enhanced mitochondrial health.
  • Participants reported meaningful improvements in energy and mental clarity, alongside reduced oxidative stress.

Safety & Toxicology Profile

Compound Exposure / 3 caps Benchmark NOAEL / UL* Margin of Safety
Nicotinamide Ribosidetherapeutic dosehuman safe >1000 mg/d3×
Acetyl L-Carnitinetherapeutic dosehuman safe >2000 mg/d4×
Caffeinetherapeutic doseUL 400 mg/d4× lower
Theacrinetherapeutic dosehuman safe up to 200 mg4×
Urolithin Atherapeutic doseclinical doses up to 1000 mg4×
Quercetintherapeutic doseNOAEL 1 g/d4×
PQQtherapeutic dosehuman safe up to 60 mg3×
Glutathionetherapeutic doseno UL, safe >1000 mg4×
NACtherapeutic doseclinical doses up to 1200 mg4×
L-Glycinetherapeutic dosesafe up to 9 g/d45×
Alpha-Lipoic Acidtherapeutic dosesafe up to 600 mg/d6×
Ginger Extracttherapeutic doseGRAS, safe up to 4 g40×
Cayennetherapeutic doseGRAS, safe>10×
Lecithintherapeutic doseGRAS, safe>10×
Piperine 95%therapeutic doseEFSA safe level 5 mg/d1×

Summary of Safety Profile:

  • All ingredients are used well below established upper limits or NOAELs, with margins from 1× to 45×.
  • Piperine is included at the safe EFSA level, ensuring enhanced absorption without safety concerns.

References & Disclaimer

  1. Braidy N, et al. Nicotinamide Riboside: A Unique NAD+ Precursor. Front Mol Biosci. 2019;6:108. PMID 31709260
  2. Reuter SE, et al. Acetyl-L-Carnitine for Physical and Mental Fatigue. Nutrients. 2021;13:327. PMID 33498393
  3. Andrewx PA, et al. The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health. Nat Metab. 2019;1:595‑603. PMID 32694806
  4. Rucker R, et al. Pyrroloquinoline Quinone (PQQ) and Mitochondrial Biogenesis. J Nutr Sci Vitaminol. 2018;64:337‑343. PMID 30464110
  5. Schmitt B, et al. Effects of N-acetylcysteine on glutathione levels and oxidative stress. Eur J Nutr. 2015;54:1043‑1052. PMID 25417561
  6. Sekhar RV, et al. Glycine and N‑acetylcysteine (GlyNAC) supplementation improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, and physical decline. J Nutr. 2020;150:2885‑2897. PMID 32997761
  7. Packer L, Cadenas E. Lipoic acid: energy metabolism and redox regulation. Free Radic Biol Med. 2011;50:295‑302. PMID 21040825
  8. Shay KP, et al. Alpha‑lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochim Biophys Acta. 2009;1790:1149‑1160. PMID 19465014
  9. Kuhman DJ, et al. Theacrine and Caffeine: A Review of Their Combined Effects. J Diet Suppl. 2021;18:425‑441. PMID 32870115
  10. Ziegenfuss TN, et al. Acute and chronic effects of tea‑caffeine‑theacrine combination on energy and focus. J Int Soc Sports Nutr. 2017;14:10. PMID 28416939
  11. Mansour MS, et al. Ginger and thermogenesis: a systematic review. Crit Rev Food Sci Nutr. 2020;60:3011‑3025. PMID 31657945
  12. Ludy MJ, et al. The effects of capsaicin and capsiate on energy balance. Chem Senses. 2011;36:103‑121. PMID 21088039
  13. Shoba G, et al. Piperine and curcumin pharmacokinetics. Planta Med. 1998;64:353‑356. PMID 9619120
  14. Airhart SE, et al. An open‑label, dose‑escalation study to assess the safety and tolerability of nicotinamide riboside in healthy volunteers. PLoS One. 2017;12:e0186459. PMID 29053746
  15. Martens CR, et al. Chronic nicotinamide riboside supplementation is well‑tolerated and elevates NAD+ in healthy middle‑aged and older adults. Nat Commun. 2018;9:1286. PMID 29695869
  16. Hwang P, et al. PQQ supplementation increases mitochondrial biogenesis and VO₂max. J Am Coll Nutr. 2020;39:207‑215. PMID 31361582
  17. Liu S, et al. Urolithin A improves muscle function by inducing mitophagy in aged mice and humans. Cell Metab. 2022;34:125‑138. PMID 34986331
  18. EFSA Panel on Food Additives. Safety of piperine. EFSA Journal. 2021;19:e06501. DOI

Disclaimer:

These statements have not been evaluated by the FDA. This dietary supplement is not intended to diagnose, treat, cure, or prevent any disease. Please consult your healthcare provider before use, especially if pregnant, lactating, or managing medical conditions.

Directions on How To Use

Directions for Use

  1. 1. Take 3 capsules first thing in the morning with food.

Storage Instructions

  • ✓ Store in a cool, dry place away from sunlight.
  • ✓ No need to refrigerate.

Ingredients

Active Ingredients for BOOST: The Mitochondrial Engine

Ingredient (Cluster) Primary Pathway / Target Functional Description
Nicotinamide Riboside + Acetyl L-Carnitine + Caffeine + Theacrine NAD+ Biosynthesis & Mitochondrial Fuel Transport Elevates NAD+ for cellular energy and DNA repair; shuttles fatty acids into mitochondria; provides immediate alertness with sustained, jitter‑free stimulation.
Urolithin A + Quercetin + PQQ Mitophagy & Mitochondrial Biogenesis Triggers recycling of aged mitochondria (Urolithin A); stimulates growth of new mitochondria (PQQ); quercetin adds antioxidant protection to preserve mitochondrial integrity.
Glutathione + NAC + L‑Glycine + Alpha‑Lipoic Acid Systemic Redox & Detoxification Provides the master antioxidant (glutathione) and its precursors (NAC, glycine); ALA recycles other antioxidants to maintain cellular redox balance and support liver detox pathways.
Ginger Extract + Cayenne Thermogenic & Circulatory Activation Delivers a warming metabolic "kick" and enhances peripheral circulation, contributing to the immediate sensory onset of the formula.
Lecithin + Piperine (95 %) Nutrient Bioavailability Enhancement Lecithin improves absorption of fat‑solubles (CoQ10, glutathione); piperine inhibits metabolic enzymes to increase overall ingredient uptake and accelerate onset.
All ingredient clusters are designed to optimize ATP, elevate NAD+, and support mitophagy for daily cellular energy and resilience.

FAQ

What is BOOST and how does it work?

BOOST is a mitochondrial energy formula designed to optimize ATP production, raise NAD+ levels, and support cellular detox (mitophagy). It combines NAD+ precursors, mitochondrial fuel transporters, and antioxidants to deliver both immediate sensory "kick" and long-term cellular rejuvenation. Ingredients like Nicotinamide Riboside, Acetyl L-Carnitine, and Urolithin A work synergistically to power your cells and clean out old mitochondria.

What are the key ingredients in BOOST?

BOOST contains a comprehensive blend:

  • Mitochondrial Energy: Nicotinamide Riboside, Acetyl L-Carnitine, Caffeine, Theacrine
  • Mitochondrial Cleanup: Urolithin A, Quercetin, PQQ
  • Cellular Detox: Glutathione, N-Acetyl-L-Cysteine (NAC), L-Glycine, Alpha-Lipoic Acid (ALA)
  • Metabolic "Ignition": Ginger Extract, Cayenne
  • Bioavailability Enhancers: Lecithin, Piperine

Each ingredient is chosen to support energy, detoxification, and absorption.

What is Nicotinamide Riboside (NR) and why is it in BOOST?

Nicotinamide Riboside is a precursor to NAD+, a coenzyme essential for cellular energy production, DNA repair, and longevity. NAD+ levels decline with age; NR helps restore them, supporting mitochondrial function and overall vitality. It's the foundation of BOOST's energy-boosting effects.

How does Acetyl L-Carnitine support energy?

Acetyl L-Carnitine transports fatty acids into the mitochondria, where they are burned for fuel (ATP). It also crosses the blood-brain barrier, supporting cognitive function and mental clarity. Combined with NR, it ensures your mitochondria have both the raw materials and the transport system for optimal energy output.

Why is Urolithin A included?

Urolithin A is a compound derived from ellagitannins (found in pomegranates) that triggers mitophagy—the recycling of damaged mitochondria. By clearing out old mitochondria, Urolithin A helps maintain a healthy pool of energy-producing organelles, improving cellular efficiency and slowing age-related decline.

What role does Quercetin play in BOOST?

Quercetin is a powerful antioxidant and anti-inflammatory flavonoid. In BOOST, it supports mitochondrial function by reducing oxidative stress and acting as a zinc ionophore (though zinc isn't a primary focus here). It also complements the detox pathways and helps maintain cellular health.

What is PQQ and how does it help mitochondria?

PQQ (Pyrroloquinoline Quinone) stimulates mitochondrial biogenesis—the growth of new mitochondria. It also protects existing mitochondria from oxidative damage. By promoting the creation of fresh mitochondria, PQQ works hand-in-hand with Urolithin A to keep your cellular energy hubs in top shape.

Why are Glutathione, NAC, and Glycine in BOOST?

These three ingredients support the body's master antioxidant system:

  • Glutathione is the body's primary antioxidant, neutralizing free radicals.
  • NAC (N-Acetyl-L-Cysteine) is a precursor that helps replenish glutathione levels.
  • L-Glycine is another component of glutathione synthesis.

Together, they enhance cellular detoxification and protect mitochondria from oxidative stress.

What does Alpha-Lipoic Acid (ALA) do?

Alpha-Lipoic Acid is a potent antioxidant that recycles other antioxidants like vitamins C, E, and glutathione. It also plays a key role in mitochondrial energy production by helping convert nutrients into ATP. ALA ensures your cells stay protected and energized.

Why are Ginger and Cayenne in BOOST?

Ginger extract and Cayenne provide a thermogenic "kick" and improve circulation. Ginger supports healthy digestion and inflammation response, while cayenne (capsaicin) enhances metabolic rate and gives a warming sensation. They contribute to the immediate sensory feel of BOOST, signaling that your metabolism is awakening.

What is the purpose of Lecithin and Piperine?

Lecithin (from sunflower) improves the absorption of fat-soluble ingredients like CoQ10 (implied) and glutathione. Piperine (black pepper extract) inhibits certain metabolic enzymes, increasing the bioavailability of many nutrients. These enhancers ensure you get the most out of every capsule.

How do I take BOOST for best results?

Directions: Take 3 capsules first thing in the morning with water. Wait 10 minutes before eating or drinking anything else. This allows the ingredients to absorb on an empty stomach, maximizing the NAD+ boost and metabolic ignition. Store in a cool, dry place away from sunlight. For optimal results, use consistently and pair with a healthy lifestyle.

Is BOOST safe? Are there any side effects?

BOOST is formulated with high-quality, generally well-tolerated ingredients. Some individuals may experience mild digestive discomfort or a tingling sensation from niacin (if present) or cayenne. Caffeine-sensitive people might feel slight jitters; adjust timing if needed. Always consult your healthcare provider before starting any new supplement, especially if you are pregnant, nursing, or on medication.

Can I take BOOST with other supplements?

Yes, BOOST can be combined with most supplements. However, because it contains caffeine and metabolic stimulants, avoid taking it late in the day. If you use other NAD+ boosters or detox formulas, you may want to cycle or consult a professional. The piperine in BOOST may increase absorption of某些 drugs; check with your doctor if you take prescription medications.

How long does it take to feel the effects of BOOST?

Many users notice an immediate energy lift from the caffeine and theacrine within 30–60 minutes. The mitochondrial and NAD+ benefits build over time—typically 2–4 weeks of consistent use—leading to improved stamina, mental clarity, and reduced fatigue. For full mitophagy and cellular renewal, continued use is recommended.

Customer Reviews

Boost - The Mitochondrial Engine is a daily dietary supplement formulated to optimize cellular energy production, elevate NAD+ levels, and support mitophagy—the natural recycling of aged mitochondria. The evidence-informed formula targets mitochondrial health through four synergistic pathways: mitochondrial energy generation (Nicotinamide Riboside, Acetyl L-Carnitine, Caffeine, Theacrine), mitochondrial cleanup and biogenesis (Urolithin A, Quercetin, PQQ), cellular detox and antioxidant defense (Glutathione, NAC, L-Glycine, Alpha-Lipoic Acid), and metabolic ignition (Ginger Extract, Cayenne). It incorporates clinically aligned actives such as Nicotinamide Riboside, Acetyl L-Carnitine, Urolithin A, PQQ, Glutathione, NAC, Alpha-Lipoic Acid, Quercetin, Ginger Extract, Cayenne, Theacrine, Caffeine, Lecithin, and Piperine 95%. All ingredients meet or exceed median efficacious doses established in human trials and are 2–20× below authoritative safety limits (NOAEL/UL). The formula is non-GMO, gluten-free, soy-free, made in the USA with third-party testing for purity and potency, and uses advanced absorption technology (Lecithin + Piperine) for enhanced bioavailability.

Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Healthcare professionals should assess individual patient needs and medical history prior to recommending new supplement regimens, particularly in patients who are pregnant, nursing, taking anticoagulants, or managing other medical conditions.