
Ingredients
Active Ingredients for PainRelief™ from immunizeLABS
| Ingredient | Pathway | Description |
|---|---|---|
| Curcumin phytosome + Piperine | COX-2 / NF-κB | Rapid anti-inflammatory with ~30× enhanced absorption. |
| Boswellia (65 % AKBA) | 5-LOX | Potent leukotriene blocker; synergizes with curcumin. |
| White Willow Bark (salicin) | COX-1 | Natural aspirin analogue; gentler on the gut. |
| Gingerols + Eugenol | TRPV1 desensitisation | Blunts burning pain; eugenol adds topical anaesthesia. |
| Ultra-micronised PEA | PPAR-α / Micro-glial calming | Rebalances over-active nerves; pairs with agmatine. |
| Agmatine sulfate + Magnesium glycinate | NMDA modulation | Dual Ca²⁺/glutamate gating; lowers central sensitisation. |
| DL-Phenylalanine (DLPA) | Endorphin & Dopamine | Slows enkephalin breakdown for mood-lifted analgesia. |
| Bromelain | Proteolytic anti-edema | Clears fibrin plugs; enhances curcumin tissue penetration. |
| N-Acetyl-Cysteine + MSM + Astaxanthin | Antioxidant / Redox | Rebuilds glutathione and quenches ROS for faster recovery. |
| Rhodiola rosea (rosavins) | HPA-axis adaptogen | Boosts stress resilience and reduces fatigue. |
FAQ
PainRelief Frequently Asked Questions
How fast will PainRelief start working compared with ibuprofen?
Most users feel relief in 20–30 minutes thanks to fast-acting gingerols and eugenol, matching or beating ibuprofen without gut irritation.
Is PainRelief strong enough for chronic back or joint pain?
Yes. Curcumin, Boswellia & willow-salicin control COX/5-LOX while ultra-micronised PEA calms nerves—rivaling NSAIDs in clinical studies.
Will the formula make me drowsy or impair focus?
No. Sedating herbs were excluded; Rhodiola supports clear alertness.
What makes PainRelief different from regular turmeric capsules?
Phytosome-curcumin with piperine & lecithin boosts absorption ≈30× and is paired with complementary anti-inflammatory & neuro-calming actives.
Is PainRelief safe for everyday long-term use?
Yes—actives sit 2–16× below NOAEL/UL levels; vegan, gluten-free, lab-tested.
Can I take PainRelief alongside my current NSAID?
You can overlap initially; consult your doctor if on anticoagulants—salicin & bromelain may enhance blood-thinning.
How does the formula target nerve or shooting pains?
PEA, agmatine & magnesium calm NMDA receptors & micro-glia—mechanisms NSAIDs don’t address.
Is there scientific proof behind the ingredients?
Over 32 peer-reviewed studies confirm each pathway; full bibliography available.
How many capsules per dose and how often?
Take 4 capsules once daily; for acute flares, add 2 more every 6–8 h (max 6/day).
When should I expect full-spectrum results?
Noticeable relief within an hour; continued improvement over 1–2 weeks.
Is PainRelief safe for children?
Formulated for adults (18+). Consult a pediatrician before use in children.
Can I use PainRelief if I’m pregnant or breastfeeding?
Not recommended; limited safety data for these groups. Consult a healthcare provider.
Are there any contraindications or medication interactions?
Avoid if allergic to salicylates, active ulcers, or on blood thinners without supervision. Check with provider if on MAO-Is or high-dose antidepressants.
What causes lower back pain?
Muscle strains, herniated discs, arthritis or spinal issues; triggers include poor posture, heavy lifting & prolonged sitting.
References: NIAMS; Mayo Clinic
How to relieve sciatica pain?
Targeted stretches, massage, heat/ice therapy; piriformis stretches & myofascial release are effective.
References: Healthline; HSSH Health
What helps knee pain?
RICE method, strength training, proper footwear; aquatic exercises for arthritis.
References: Cleveland Clinic; Houston Methodist
Why do I have shoulder pain?
Rotator cuff injuries, frozen shoulder, arthritis or referred neck pain; posture correction & exercises help.
References: Johns Hopkins; AANS
How to treat herniated disc pain?
Physical therapy, epidural steroids, core strengthening; surgery if conservative fails.
References: HSS; MedlinePlus
What causes chest pain?
Cardiac issues, GERD, musculoskeletal strain; seek immediate evaluation for sudden severe pain.
References: Cleveland Clinic; Johns Hopkins
How to stop headaches?
Identify triggers, relaxation techniques, OTC meds; chronic headaches require medical care.
References: Mayo Clinic; Johns Hopkins
What relieves bursitis pain?
Rest, NSAIDs, protective padding; corticosteroids for persistent cases.
References: Houston Methodist; Cleveland Clinic
Why do I have neck pain?
Poor posture, whiplash or cervical spondylosis; ergonomic adjustments & exercises help.
References: Johns Hopkins; AANS
How to manage chronic back pain?
Physical therapy, CBT, targeted exercises; multidisciplinary pain programs.
References: NIAMS; HSS
What causes leg cramps?
Dehydration, electrolyte imbalance, overuse; stretching & hydration help.
References: Mayo Clinic; Johns Hopkins
How to relieve toothache pain?
Saltwater rinses, cold compresses, OTC pain relievers; dental care if persistent.
References: Cleveland Clinic; Johns Hopkins
What causes abdominal pain?
Digestive issues, appendicitis, menstrual cramps; seek care if severe.
References: Mayo Clinic; Johns Hopkins
How to treat ear pain?
Ear drops, warm compresses, OTC relievers; antibiotics for infections.
References: Mayo Clinic; Johns Hopkins
What helps sore throat pain?
Warm liquids, lozenges, OTC relievers; antibiotics for bacterial infections.
References: Cleveland Clinic; Johns Hopkins
How to reduce testicular pain?
Supportive underwear, cold compresses, OTC relievers; medical evaluation if needed.
References: Mayo Clinic; Johns Hopkins
What causes wrist pain?
Carpal tunnel, arthritis, repetitive strain; rest, ice, ergonomic adjustments.
References: Johns Hopkins; AANS
How to manage pelvic pain?
Pelvic floor exercises, therapy & pain programs; evaluate underlying issues.
References: Mayo Clinic; Johns Hopkins
Why do I have groin pain?
Muscle strains, hernias, referred back pain; rest & support garments.
References: Cleveland Clinic; Johns Hopkins
How to relieve breast pain?
Warm compresses, supportive bras, OTC relievers; hormonal factors.
References: Mayo Clinic
Customer Reviews
PainRelief™ Multimodal is a fast-acting, all-natural dietary supplement formulated to support the relief of aches in muscles and joints, ease inflamed back and neck, and improve mobility and flexibility. The evidence-informed formula targets pain through eight synergistic pathways—including COX/5-LOX inhibition, TRPV1 desensitisation, NMDA modulation, and PPAR-α activation—to calm overactive pain channels without sedation or mental fog. It incorporates clinically aligned actives such as Curcumin phytosome with piperine for enhanced absorption, Boswellia AKBA, White Willow bark, Gingerols, ultra-micronised PEA, Agmatine sulfate, DL-Phenylalanine, Bromelain, N-Acetyl-Cysteine, MSM, Astaxanthin, and Rhodiola rosea. All ingredients meet or exceed median efficacious doses established in human trials and are 2–16× below authoritative safety limits (NOAEL/UL). The formula is non-GMO, gluten-free, soy-free, and made in the USA with third-party testing for purity and potency.
Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Healthcare professionals should assess individual patient needs and medical history prior to recommending new supplement regimens, particularly in patients who are pregnant, nursing, taking anticoagulants, or managing other medical conditions.