• BreatheEasy RX Seasonal Comfort Nasal Spray bottle with metered-dose pump
  • BreatheEasy RX Nasal Spray with Rosmarinic acid from Perilla leaf
  • BreatheEasy Rx Nasal Spray tag for virus and anti-histamine protection
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BreatheEasy RX – Advanced Seasonal Comfort Nasal Spray

  • Feel it in seconds
  • Up to 6 hours of comfort
  • Rosmarinic acid for seasonal allergy comfort
  • Drug-free & non-addictive
  • 10 Published Studies
  • 4.8/5 (44 reviews) ›
More Than Saline.
Cleanses. Hydrates. Supports Seasonal Allergy Comfort – for up to 6 Hours.
  • Comfort in Seconds: Menthol Lactate + Alpha Bisabolol deliver a cooling, soothing sensation on contact.
  • Seasonal Allergy Comfort: Rosmarinic acid from Perilla leaf – a plant polyphenol studied in a randomized controlled trial for seasonal allergy comfort.
  • 6-Hour Hydration (Not 15 Minutes): A multi-depth moisture film that saline can't match.
  • Breaks Down What Saline Can't Reach: Penetrates stubborn nasal biofilm – 99.99% cleansing in 30s, lab tested.
  • Zero Rebound. Zero Drowsiness. No Bitter Taste: Use daily with no dependency risk.
  • Gentle Enough for Every Day: 95% reported immediate comfort in tolerance testing.

BreatheEasy RX – Advanced Seasonal Comfort Nasal Spray

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As Seen In:

  • Marie Claire
  • TrendHunter
  • Authority Magazine
  • WGN9 Chicago's Very Own
  • Wellness Magazine
  • Alternative Medicine
  • Marie Claire
  • TrendHunter
  • Authority Magazine
  • WGN9 Chicago's Very Own
  • Wellness Magazine
  • Alternative Medicine
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12 active ingredients – including Rosmarinic acid from Perilla leaf – for broad-spectrum nasal cleansing plus seasonal allergy comfort that lasts up to 6 hours

For seasonal allergy sufferers tired of steroid sprays that take days to work, drowsy antihistamines, and decongestants you can only use for 3 days.

99.99% Broad-spectrum cleansing in 30s
RCT Rosmarinic acid · seasonal allergy
Seasonal allergy comfort
Steroid-free & drug-free
Rosmarinic acid from Perilla leaf
10 Published Studies
44+ Verified Reviews


Is BreatheEasy RX For You?

  • ✓ Want comfort in seconds, not days? No waiting period, no daily buildup – a cooling, soothing sensation the moment it contacts your nasal passages.
  • ✓ Want seasonal allergy comfort without drowsiness or aftertaste? Drug-free – zero drowsiness, zero bitter taste, every time.
  • ✓ Want something you can use every day, indefinitely? Non-habit-forming – use it as often as you need, for as long as you need.
  • ✓ Want broad-spectrum cleansing and seasonal allergy comfort in one spray? 12 active ingredients including Rosmarinic acid from Perilla leaf – cleansing, hydration, and seasonal comfort together.
  • ✓ Want a natural approach without compromising on science? 12 active ingredients. 10 peer-reviewed studies. Internationally recognized test protocols (ASTM, ISO, CDC).

The Rosmarinic Acid Difference

Rosmarinic acid is a plant-based polyphenol extracted from Perilla leaf (Perilla frutescens). In a randomized, double-blind, placebo-controlled clinical trial (Takano et al., 2004 – PubMed 14988517), Perilla extract enriched for rosmarinic acid significantly improved seasonal allergy symptom scores – including nasal, eye, and overall symptom scores – compared to placebo over 21 days.

A studied amount of rosmarinic acid, delivered directly to nasal passages where it matters most – not through your digestive system like oral supplements.

Why this matters: Rosmarinic acid works through multiple natural pathways to support seasonal allergy comfort – delivered directly where it's needed, with no drowsiness and no daily buildup.

How BreatheEasy RX Works in 3 Steps

Step 1 – Instant Comfort (seconds): Menthol Lactate and Alpha Bisabolol deliver a cooling, soothing sensation on contact. 95% reported immediate comfort in tolerance testing.
Step 2 – Deep Cleansing (30 seconds): Monolaurin and Tri-iodide deliver broad-spectrum cleansing while HPBCD penetrates biofilm that saline rinses miss. Lab testing: 99.99% cleansing in 30 seconds (ASTM E1052).
Step 3 – Lasting Comfort (up to 6 hours): Glycerin, Sodium Hyaluronate, and D-Panthenol create a hydrating film for hours – not the 15–30 minutes you get from saline. Rosmarinic acid provides ongoing seasonal comfort support with regular use.

How Does BreatheEasy RX Compare?

Broad-spectrum cleansing plus Rosmarinic acid from Perilla leaf for seasonal allergy comfort. Based on typical use (4 sprays/day).

FeatureBreatheEasy RXLeading Steroid SprayLeading Antihistamine SprayLeading Decongestant Spray
Type12-ingredient botanicalCorticosteroid drugAntihistamine drugDecongestant drug
Seasonal allergy comfort✓ Rosmarinic acid (RCT-studied)Steroid-basedDrug-based✗
Active ingredients12111
OnsetSeconds12–24 hours15–30 minSeconds
DurationUp to 6 hours24 hrs (must use daily)12 hours4–6 hrs (max 3 days)
Broad-spectrum cleansing✓ 99.99% in 30s✗✗✗
Steroid-free✓✗ Steroid✓✓
Drug-free✓✗✗✗
No drowsiness✓✓✗ 12%✓
No rebound✓✓✓✗ After 3 days
Cost/day (4 sprays)$0.66/day$0.73/day$0.36/day$3.67/day*

*Leading decongestant sprays are limited to 3 days max due to rebound dependency. Effective cost = bottle price ÷ 3 usable days.

What Seasonal Allergy Relief Actually Costs

Leading OTC steroid spray $18–$22/month (1 ingredient)
Leading OTC antihistamine spray $16–$29/month (drowsiness risk)
Rosmarinic acid oral supplement $20–$35/month (oral, not direct nasal)
BreatheEasy RX (12 ingredients + Rosmarinic acid) ~$0.66/day

Less than a cup of coffee – for 12-ingredient nasal comfort with direct Rosmarinic acid delivery.

10 Published Studies. Real Lab Data. No Guesswork.

Every claim on this page is backed by peer-reviewed research and internationally recognized test protocols (ASTM, ISO, CDC).

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Discover the Science of BreatheEasy RX

What the Testing Proved

  • 95% of subjects reported clear breathing and reduced irritation — immediately. Not after a week. Not after a bottle. On first use. (In-vivo tolerance study)
  • 3.3-log₁₀ biofilm reduction with just two sprays. That sticky buildup inside your nose that saline can't touch? BreatheEasy RX's HPBCD transport system breaks through it. (CDC Biofilm Model, 24 h)
  • ≥ 4-log₁₀ broad-spectrum cleansing in 30 seconds. Monolaurin and Tri-iodide (I3−) deliver rapid, broad-spectrum action — not in minutes, in half a minute. (ASTM E1052)
  • Rosmarinic acid significantly improved seasonal comfort scores vs placebo. In a randomized, double-blind, placebo-controlled trial, Perilla extract enriched for rosmarinic acid improved nasal comfort, eye comfort, and overall wellness over 21 days. (Takano et al., 2004 — PubMed 14988517)

The bottom line: BreatheEasy RX delivers everything BreatheEasy does — broad-spectrum cleansing, biofilm penetration, hours of hydration — plus Rosmarinic acid from Perilla leaf for targeted seasonal comfort.

The Rosmarinic Acid Advantage

Rosmarinic acid is a plant-based polyphenol extracted from Perilla leaf (Perilla frutescens). Unlike steroids that suppress broadly or antihistamine drugs that block one pathway and cause drowsiness, rosmarinic acid works through multiple natural pathways to support seasonal nasal comfort — without the trade-offs.

  • RCT-studied: A peer-reviewed randomized controlled trial (Takano et al., 2004) showed Perilla extract enriched for rosmarinic acid significantly improved seasonal comfort scores compared to placebo over 21 days.
  • Direct nasal delivery: Unlike oral rosmarinic acid supplements that pass through your digestive system, BreatheEasy RX delivers it directly where it matters — your nasal passages.
  • Excellent safety profile: Human oral studies and preclinical nasal studies report no serious adverse effects. Used at conservative, studied levels.

How Each Ingredient Earns Its Place

Every ingredient in BreatheEasy RX has a specific job. Nothing is filler.

  • Soothing + cooling (instant): Alpha Bisabolol Liposome and Menthol Lactate reduce nasal irritation and deliver a cooling open-breathing sensation within 10 seconds.
  • Congestion relief + deep hydration: Glycerin and D-Panthenol maintain your mucosal-moisture barrier and support tissue comfort. This is why breathing stays clear for hours, not minutes.
  • Biofilm disruption: HPBCD acts as a molecular transport vehicle, carrying active ingredients through the biofilm barrier — achieving 3.3-log₁₀ reduction of stubborn nasal buildup in lab testing.
  • Broad-spectrum cleansing (30 seconds): Monolaurin disrupts the lipid membranes of common nasal microorganisms. Tri-iodide (I3−) oxidizes on contact. Together: ≥ 4-log₁₀ reduction in 30 seconds.
  • Seasonal comfort support: Rosmarinic acid from Perilla leaf — a plant-based polyphenol that supports nasal tissue comfort during seasonal changes. The ingredient that makes RX different from BreatheEasy.

The bottom line: One spray soothes, cleans, hydrates, breaks down buildup, and supports seasonal comfort — in the time it takes to tie your shoes.

Why Ingredients Are Paired (Not Random)

  • Glycerin + Sodium Hyaluronate: Glycerin hydrates the surface. Hyaluronate pulls moisture deep into tissue. Together = multi-depth hydration that lasts up to 6 hours (vs. 15–30 min for saline alone).
  • Alpha Bisabolol Liposome + D-Panthenol: Bisabolol calms irritation. D-Panthenol repairs tissue. The liposomal delivery pushes both deeper into inflamed tissue than either could reach alone.
  • Monolaurin + Sodium Chloride: Monolaurin disrupts lipid membranes. Sodium Chloride optimizes the ionic environment so Monolaurin works faster. Neither is as effective without the other.
  • Tri-iodide + HPBCD: Tri-iodide is powerful but unstable. HPBCD stabilizes it and enhances solubility — so you get consistent, rapid action every spray, not just the first one.
  • Rosmarinic Acid + Alpha Bisabolol: Rosmarinic acid supports seasonal comfort through multiple natural pathways. Alpha Bisabolol calms irritation on contact. Together they provide both immediate soothing and ongoing seasonal support.

The bottom line: Every pairing exists because A makes B work better. Remove one and the formula gets weaker. This is why BreatheEasy RX uses 12 active ingredients — not 1 or 2.

Lab Performance Data

Test Protocol What Was Tested Contact Time Result (Log₁₀ Reduction)
ASTM E1052 Enveloped microorganisms (surrogate) 30 s 4.0 (99.99%)
ASTM E1052 Gram-positive bacteria 30 s 4.0 (99.99%)
ASTM E1052 Common nasal yeast 30 s 3.2 (99.94%)
CDC Biofilm Model Mixed nasal biofilm 2 × 30 s 3.3 (99.95%)
RCT (Takano et al., 2004) Seasonal comfort scores (rosmarinic acid vs placebo) 21 days Significant improvement vs placebo

Why this matters: A 4-log reduction means 99.99% of targeted microorganisms are eliminated in the test. Most saline sprays achieve 0-log — they rinse mechanically but have zero active cleansing. BreatheEasy RX does both — plus delivers Rosmarinic acid for seasonal comfort that no competitor spray offers.

Safety: Every Ingredient Far Below Limits

Ingredient Your Exposure (5% swallow) Safety Limit How Far Below
Iodine (Tri-iodide) Far below UL 1 mg/day (IOM) 20× below limit
Glycerin Far below GRAS GRAS — no limit 500× below
HPBCD Far below GRAS ~1.2 g/day (food use) 2,500× below
Monolaurin Very low GRAS — high threshold 4,000× below
Rosmarinic Acid Well below studied doses Excellent safety in human oral studies Wide margin — no serious adverse effects reported

Why this matters: Even if you accidentally swallowed 5% of every spray for a year, you'd still be thousands of times below any safety threshold. BreatheEasy RX is safe for daily use — that's not a marketing claim, it's math. Rosmarinic acid has an excellent safety profile across multiple human and preclinical studies.

Comfort Confirmed by Human Testing

ISO 10993-10 nasal irritation and in-vivo tolerance studies confirm: non-irritant. No burning, no stinging, no dryness. 95% of subjects reported immediate comfort.

This is a pH-balanced (6.2), isotonic, alcohol-free formula with Aloe Vera and Chamomile. It's designed to feel good the moment it hits your nasal passages — not just work in the background.

Published References

  1. ISO 10993-10. Irritation & mucosal sensitisation testing.
  2. ASTM E2315-16. Standard suspension test.
  3. ASTM E1052-20. Standard test method for microbial activity.
  4. Meister TL et al., 2021. Nasal spray essential oil activity.
  5. Pavan R et al., 2021. Bromelain for sinus and nasal comfort.
  6. Gökhan S et al., 2022. Intranasal acetylcysteine in nasal congestion.
  7. Jayasinghe L et al., 2024. Monolaurin nano-emulsion nasal activity.
  8. Martins P et al., 2022. Intranasal xylitol as nasal comfort adjunct.
  9. Challacombe SJ et al., 2024. Povidone-iodine nasal spray trial.
  10. Takano H et al., 2004. Perilla frutescens extract enriched for rosmarinic acid — randomized controlled trial for seasonal comfort.

10 peer-reviewed publications. Internationally recognized test protocols (ISO, ASTM, CDC). Every claim above has a citation. If you want to verify any of them, the links go directly to PubMed and official standards bodies.

Directions to Use

BreatheEasy RX: Daily Use Instructions

  1. Use as often as needed. Ideal first thing in the morning, before bed for a better night of sleep, and before a workout. Power lifters use this before a major lift for a boost!
  2. Best time to use: First thing in the morning and before bed — the Rosmarinic acid supports nasal tissue comfort overnight.
  3. Be careful — very potent. Wait a few seconds before repeating in the second nostril.
  4. Exhale first. Breathe deeply while squirting once into one nostril.

Store in a cool, dry place away from sunlight. Rosmarinic acid is light-sensitive; keep bottle tightly closed when not in use.

Ingredients

All our ingredients are of the highest quality and organic where possible

Ingredients & Functions

Ingredient Function
Purified Water Solvent & carrier
Glycerin Primary humectant for moisture barrier support
Sodium Chloride Osmotic balance & isotonicity
Tri-iodide (KI + I₂) Broad-spectrum cleansing agent
Monolaurin Lipid membrane disruptor — supports broad-spectrum nasal cleansing
Hydroxypropyl-β-Cyclodextrin (HPBCD) Solubilizer & stabilizer for actives
D-Panthenol (Pro-Vitamin B5) Humectant & skin barrier repair
Alpha Bisabolol Liposome Soothing & calming agent
Menthol Lactate & Peppermint Oil Cooling sensation & airway comfort
Sodium Citrate pH buffer & stability agent
Sodium Hyaluronate Deep hydration & mucosal coating
Rosmarinic Acid (from Perilla leaf) Plant-based polyphenol studied in a peer-reviewed RCT for seasonal nasal comfort. Supports nasal tissue comfort during seasonal changes. The ingredient that makes BreatheEasy RX different from BreatheEasy.

In Plain English: Each listed ingredient has a specific role — from cleansing your nasal passages to hydrating and calming them for hours of comfort. Rosmarinic acid adds targeted seasonal comfort support that standard BreatheEasy doesn't include.

FAQ

BreatheEasy RX: Frequently Asked Questions

1. What makes BreatheEasy RX different from saline spray?

Saline sprays rinse and hydrate for 15–30 minutes. Then they dry up. BreatheEasy RX uses 12 active ingredients — including Rosmarinic acid from Perilla leaf — to cleanse, hydrate, soothe irritation, and break down nasal buildup. The hydrating film lasts up to 6 hours. Think of it this way: saline is a garden hose. BreatheEasy RX is a pressure washer that also applies a protective coating.

2. How fast does it work?

You'll feel it in 10 seconds. Menthol Lactate delivers a cooling, open-breathing sensation almost immediately. The full formulation reaches peak cleansing activity in 30 seconds. Most users say they notice clearer breathing before they've finished both nostrils.

3. How long does it last?

Up to 6 hours. Glycerin and Betaine form a hydrating film that maintains moisture and comfort far beyond what saline achieves (typically 15–30 minutes). Use twice daily — morning and night — and you're covered for most of your waking hours.

4. How do I use it?

30 seconds, twice a day:

  • Exhale first
  • Insert nozzle, breathe in gently while pressing once
  • Wait 5 seconds for the Menthol Lactate to open the airway
  • Repeat in the second nostril

Don't blow your nose immediately after — let the formulation coat your nasal passages. Best results: first thing in the morning and before bed — the Rosmarinic acid supports nasal tissue comfort overnight.

5. Will it sting or burn?

No. pH-balanced at 6.2, isotonic, with Aloe Vera and Chamomile. No alcohol, no chlorine. 95% of test subjects in the in-vivo study reported comfort on first use. If you've been burned by other sprays before, BreatheEasy RX was specifically formulated to avoid that.

6. Is it addictive? Will I get rebound congestion?

No. BreatheEasy RX contains zero vasoconstrictors (oxymetazoline, phenylephrine). Those are what cause rebound congestion in drugstore decongestants. BreatheEasy RX is drug-free — you can use it as often as needed with zero dependency risk.

7. What is "biofilm" and why should I care?

Biofilm is a sticky, protein-rich layer that builds up inside your nasal passages. It's like plaque on your teeth — but in your nose. Saline can't break through it. It just washes over the top. BreatheEasy RX's Hydroxypropyl-β-Cyclodextrin acts as a molecular transport vehicle that carries active ingredients through the biofilm. Lab testing shows a 3.3-log₁₀ reduction — that's 99.95% of the buildup disrupted in two sprays.

8. My nose is always dry. Will this help?

This is exactly what BreatheEasy RX was designed for. Three hydration layers work together:

  • D-Panthenol (Pro-Vitamin B5) — supports the mucosal moisture barrier
  • Sodium Hyaluronate — pulls moisture deep into tissue
  • Glycerin — locks moisture into the surface

The result: your nasal passages stay hydrated for up to 6 hours, not the 15–30 minutes you get from saline.

9. Can I use it for congestion?

Yes. Menthol and Eucalyptus deliver an immediate cooling sensation that opens airways on contact. Glycerin and D-Panthenol hydrate the tissue to help maintain clearer nasal passages. Most users feel relief within 10 seconds — faster than menthol rubs or steam.

10. Is it safe for daily use?

Yes — by a wide margin. Every ingredient is used at levels far below established safety limits. Iodine exposure is 20× below the IOM upper limit. Monolaurin is 4,000× below its GRAS threshold. Rosmarinic acid has an excellent safety profile across human and preclinical studies. ISO 10993-10 testing confirms non-irritant status. The full safety data is in the Science section above.

11. What is Rosmarinic acid and why is it in BreatheEasy RX?

Rosmarinic acid is a plant-based polyphenol extracted from Perilla leaf (Perilla frutescens). In a peer-reviewed randomized controlled trial (Takano et al., 2004), Perilla extract enriched for rosmarinic acid significantly improved seasonal comfort scores compared to placebo over 21 days. BreatheEasy RX delivers it directly to your nasal passages — not through your digestive system like oral supplements.

12. How is BreatheEasy RX different from regular BreatheEasy?

BreatheEasy RX includes everything in BreatheEasy — all 11 original active ingredients, the same broad-spectrum cleansing, the same 6-hour hydration — plus Rosmarinic acid from Perilla leaf as the 12th ingredient, specifically for seasonal nasal comfort. If you don't need seasonal comfort support, regular BreatheEasy at $0.26/day is the better value.

13. How does BreatheEasy RX compare to Flonase?

Flonase is a corticosteroid drug with 1 active ingredient. It takes 12–24 hours for onset and requires daily use for weeks before full effect. BreatheEasy RX has 12 active ingredients, works in seconds, and costs $0.66/day vs Flonase at $0.73/day. Plus: no steroids, no drugs, broad-spectrum cleansing that Flonase doesn't offer.

14. How does BreatheEasy RX compare to Astepro?

Astepro is an antihistamine drug. It works in 15–30 minutes but causes drowsiness in 12% of users and bitter taste in 13%. BreatheEasy RX works in seconds, causes zero drowsiness and zero bitter taste, and delivers seasonal comfort through Rosmarinic acid — a plant-based approach, not a drug.

15. Is it safe for kids or pregnant adults?

Children under 12: Consult a healthcare professional before use. Pregnant/nursing: Consult your healthcare provider. The ingredients are generally recognized as safe, but individual circumstances vary.

16. Is BreatheEasy RX vegan?

Yes. Plant-derived actives (including Rosmarinic acid from Perilla leaf), GRAS preservatives, no steroids, no synthetic dyes, no animal products. Made in the USA since 2015.

17. Can I travel with it?

Yes. TSA-compliant size, fits in a carry-on or jacket pocket. Ideal before flights (dry cabin air), on public transit, or in hotel rooms. Many users spray before boarding and again mid-flight. Store away from direct sunlight — Rosmarinic acid is light-sensitive.

18. Where can I buy BreatheEasy RX?

Direct at immunizeLABS.com. Free shipping on US orders over $99. Made in the USA since 2015.

BreatheEasy RX Nasal Spray is a non-alcoholic, evidence-informed formulation designed to support nasal comfort and respiratory wellness. The formula combines 12 active ingredients — including broad-spectrum cleansing agents and Rosmarinic acid from Perilla leaf, a plant-based polyphenol with studied comfort and antioxidant properties. Together, these ingredients work to maintain a balanced nasal environment, support comfort during seasonal changes, and promote nasal hydration at physiological pH. Developed for routine daily use.

Disclaimer: The claims made by ImmunizeLABS have not been evaluated by the FDA. This product is not intended to diagnose, treat, prevent, or cure any disease. Healthcare professionals should evaluate patient-specific considerations prior to recommending new intranasal support products, particularly in individuals with chronic respiratory conditions, pregnancy, or concurrent medication use.